Patrick is a simple but intriguing short story, very well written. (Especially the ob/gyn doctor's vaguely nightmarish monologue stands out as excellent writing.) There is a sense of there being more to the story than is visible at first sight, and the conclusion is surprising and appropriate.
While playing, I wondered whether the story and the protagonist's name were a reference to American Psycho. Patrick doesn't have any of that novel's gruesome content, but both works are about a businessman named Patrick who keeps getting mixed up with other people. Intentional? Hard to know, unless you're the author.
The illustrations are only stock photos, but the way they form a full-screen background to the text creates a visual dimension that is rather rare in Twine games, making it feel more like a Japanese visual novel. It's probably a taste thing, but I enjoyed the effect.
While I enjoyed this as a short story, I'm not sure whether the interactivity adds much. The blurb teases us with the possibility of an alternative ending, but I haven't found one. Apart from that tantalising secret ending, Twine gives us an (Spoiler - click to show)interesting but cosmetic randomised element, and the choice whether to read or skip a part of the protagonist's story.
In short: low on the interactivity, but well worth a read for its plot and stylistic prowess.