Beyond the title, which earned a laugh from me, the game doesn't go very much farther than to detail the "stages" of hive spider infestation, and "what to expect" exactly as it says on the tin. It's nicely written, but doesn't go very much farther than that. Less a game than a slightly interactive guide that never tries for a better joke than the title.
I guess Twine is the system of choice for expressing angst, as the last few I've opened up have provided a list of "triggers"...in this case "spiders, body-horror". That's a decent way to self-regulate, I suppose.
I hate when Twine stories keep the default sugarcane theme with no modifications, and wish that authors would scale their text up if they are never going to provide a page of text that fills down past the top quarter of the screen.